Creatine is an organic acid naturally produced in your body by amino acids. It supplies energy to all cells, especially muscle cells where it increases the formation of ATP. Protein is also composed of amino acids, and a study published in the Journal of the International Society of Sports Nutrition looks at the safety of creatine supplementation while adhering to a high-protein diet.

Subjects loaded creatine or a placebo by consuming 20 grams per day for 5 days followed by a 5 gram daily maintenance dose. They continued this supplementation routine for 12 weeks while sticking to a high-protein diet. Assessments of kidney function before, during and after the program revealed no significant differences.

True Strength Moment: This study adds to a mountain of research conducted over several decades. Creatine monohydrate ranks as one of the most studied sports supplements. It has consistently been shown to safely enhance muscle size, strength and power while assisting with exercise recovery.