Nitric oxide (NO) is an important signaling molecule that acts in many tissues to regulate a diverse range of physiological and cellular processes. It’s role was first discovered by several groups who were attempting to identify the agent responsible for promoting blood vessel relaxation and regulating vascular tone.
This agent was termed endothelium-derived relaxing factor (EDRF), and was initially assumed to be a protein like most other signaling molecules. The discovery that EDRF was in fact nitric oxide – a highly reactive gas – has led to an explosion of interest in this field, resulted in over 60,000 papers published in the last ten years and won the Nobel prize in 1998.
Nitric oxide has now been demonstrated to play a role in a variety of biological processes including neurotransmission, immune defense, the regulation of cell death and cell motility.
Wondering if nitric oxide supplements will benefit you? Here are 5 reasons to take a nitric oxide supplement: